Scientific sessions
Explore the breadth of lab medicine
Scientific Sessions represent the core of ADLM 2024 with nearly 70 sessions taking place from Monday – Thursday. Scientific Sessions brings the latest scientific advances and practical tools on all aspects of laboratory medicine. They include a wide variety of formats from case-based discussion, point-counterpoint, mock courtroom, and more. Scientific Sessions also include specially developed and invited sessions from ADLM collaborations and divisions.
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Online Session Search
Browse by day to explore the details of the full scientific program to make the most of your ADLM 2024 experience.
Browse by day
Monday, July 29
Tuesday, July 30
Wednesday, July 31
Thursday, August 1
Monday, July 29
10:30 a.m. – 12 p.m.
ADLM President Invited Session
32101 Community Engagement, Research, and Healthcare: Laboratory Medicine’s Lead Role in Ensuring Health Equity
Moderator: Octavia Peck Palmer, PhD, FADLM, University of Pittsburgh Medical Center
Speakers:
- Addressing Health Equity Throughout the Total Laboratory Testing Process
Vahid Azimi, MD, Washington University
- Point-of-Care Diagnostics Provide Equitable Access to Healthcare
Omai Garner, PhD, ABMM, MT (ASCP), University of California, Los Angeles
- Interdisciplinary Approaches to Eliminate Maternal Health Inequities
Esa Davis, MD, MPH. FAAFP, University of Maryland School of Medicine
32102 Bad, Better, Best: Putting Data Visualizations to the Test
Moderator: T. Scott Isbell, PhD, DABCC, FADLM, Saint Louis University School of Medicine
Speakers:
- A Journey in Data Visualization: You be the Judge!
T. Scott Isbell, PhD, DABCC, FADLM, Saint Louis University School of Medicine
- Case Presentations: Data Visualizations for Presentations and Reports
Shannon Haymond, PhD, DABCC, FAACC, Lurie Children's
- Case Presentations: Enhancing the Accessibility of Data Visualizations
Christopher McCudden, PhD, DABCC, FACB, FCAC, The Ottawa Hospital General Campus
32103 Real-Time Mass Spectrometry: Strategies for Rapid Drug and Metabolite Detection to Enhance Clinical Decision Making
Moderator: Dennis Dietzen, PhD, DABCC, FADLM, Washington University School of Medicine
Speakers:
- Past, Present, and Future Clinical Mass Spectrometry Applications
Stephen Roper, PhD, DABCC, NRCC, Washington University School of Medicine
- Design and Implementation of Direct to Mass Spectrometry Drug Screening in Children
Stephen Roper, PhD, DABCC, NRCC, Washington University School of Medicine
- Internal vs. External Calibration for Determination of Plasma Methotrexate by LC-MS/MS
Dennis Dietzen, PhD, DABCC, FADLM, Washington University School of Medicine
- Rapid Metabolic Detection of Mutant Isocitrate Dehydrogenase Using LC-MS/MS: Application to Human Gliomas
Dennis Dietzen, PhD, DABCC, FADLM, Washington University School of Medicine
32104 Emerging Nano-Engineering Technologies for the Management of Chronic Diseases and Cancers
Moderator: Lakshmi Ramanathan, PhD, Memorial Sloan-Kettering Cancer Center
Speakers:
- Performance Characteristics and Validation in Non-Blood Analysis
Lakshmi Ramanathan, PhD, Memorial Sloan-Kettering Cancer Center
- Saliva Based Technologies for the Management of Chronic Disease and Cancer
Chamindie Punyadeera, PhD, Griffith University
- Application of Nano-Engineering Technologies in Cancer
Mijin Kim, PhD, Georgia Institute of Technology
32105 Ethical Decision Making for Laboratory Professionals
Moderator: Ann Gronowski, PhD, DABCC, Washington University School of Medicine
Speakers:
- Ethical Issues in Laboratory Medicine
Ann Gronowski, PhD, DABCC, Washington University School of Medicine
- Ethical Issues Arising From Direct-To-Consumer Genetic Testing
Valerie Gutman Koch, JD, Health Law and Policy Institute, University of Houston
32106 Is Bad Testing Better Than No Testing?
Moderator: Steven Cotten, PhD, DABCC, NRCC, FADLM, University of North Carolina at Chapel Hill
Speakers:
- Critical Crossroads: Decision Making in Clinical Testing
Sarah Hackenmueller, PhD, DABCC, FADLM, Providence Regional Laboratories
- Decision Dynamics: Testing, Requests, and Patient Care
Yachana Kataria, PhD, DABCC, Boston University Chobanian and Avedisian School of Medicine
32107 Tools for Recognizing and Eliminating Preanalytical Error
Moderator: Christopher Farnsworth, PhD, DABCC, Washington University in St. Louis
Speakers:
- Impact of Preanalytical Errors on Patient Care
Joe El-Khoury, PhD, DABCC, FADLM, Yale University
- Harnessing the Power of Modern Tools to Reduce Preanalytical Error
Christopher Farnsworth, PhD, DABCC, Washington University in St. Louis
Session Highlight
32108 Accelerating Point of Need Diagnostics to Meet the Growing Demand for Acute and Advanced Care at Home
Attend this session to explore the current and emerging opportunities to accelerate point-of-need diagnostics to meet the growing demand for acute and advanced care at home.
Moderator: Jared Conley, MD, PhD, MPH, Massachusetts General Hospital
Speakers:
- Hospital at Home: Current Diagnostic Realities and Emerging Opportunities
Jared Conley, MD, PhD, MPH, Massachusetts General Hospital
- Emergency Department at Home: Leveraging Current Technologies to Improve Rapid, Convenient Diagnosis
David Whitehead, MD, Massachusetts General Hospital
32109 The Nexus of Innovation: How Laboratory Medicine Supports Cellular and Gene Therapy Advancements
Moderator: Zhen Zhao, PhD, DABCC, FADLM, Weill Cornell Medicine
Speakers:
- Rewards and Challenges of Point-of-Care Cell Manufacturing and Delivery of Novel Gene Modified Cell Therapies
Amittha Wickrema, PhD, University of Chicago
- mRNA-Based CAR T Manufacturing and Testing
Yen-Michael Hsu, MD, PhD, University of Pittsburgh
- Characterization of a Patient’s Pre-existing Immunity to Viral Vectors in Gene Therapy: Implications and Forward Thinking
Zhen Zhao, PhD, DABCC, FADLM, Weill Cornell Medicine
Special Q&A with Wallace H. Coulter Lectureship Awardee
62001 Why We Need More Strong Clinical Trials of Laboratory Tests (Meet-the-Expert)
Moderator: David Sacks, MB ChB, FRCPath, National Institutes of Health
Speaker: Patrick Bossuyt, PhD, University of Amsterdam/Amsterdam UMC
12:30 p.m. – 2 p.m.
AMOC Chair Invited Session
32441 Operationalizing Changes to LDT Oversight: Building Roadmaps When the Rubber Hits the Road
Moderator: Mark Marzinke, PhD, DABCC, FADLM, Johns Hopkins University
Speakers:
- Developing Tools to Manage Decreased Access to LDTs
Stephen Master, MD, PhD, FADLM, Children's Hospital of Philadelphia
- LDTs as Medical Devices? Strategies for Prioritization and Regulatory Compliance
Jonathan Genzen, MD, PhD, ARUP Laboratories
- Biomarkers and Bureaucracy: Impact of FDA Regulation of Molecular Diagnostics LDTs
Eric Konnick, MD, University of Washington
32442 Unexpected Results: Using Proficiency Testing to Improve Toxicology and Pharmacogenetic Testing in Your Lab
Moderator: Christine Snozek, PhD, DABCC, FADLM, Mayo Clinic
Speakers:
- Evolution of Toxicology Proficiency Testing Programs in Response to the Changing Landscape of Drug Testing
Christine Snozek, PhD, DABCC, FADLM, Mayo Clinic
- Evolution of PGx Proficiency Testing Programs to Align With Laboratory Practice and Unmet Needs
Gwendolyn McMillin, PhD, DABCC, University of Utah/ARUP Laboratories
- Red Herrings and Writeups: Using Analytical Challenges and Expert Resources to Improve and Troubleshoot Performance
Nicholas Heger, PhD, NRCC, Tufts Medical Center
32443 Moving Beyond Sensitivity and Specificity: Showing the Value of Lab Medicine Through Outcome Measures
Moderator: Zhen Zhao, PhD, DABCC, FADLM, Weill Cornell Medicine
Speakers:
- Using Outcomes Studies/Measures to Improve the Delivery of Care
David Grenache, PhD, DABCC, MT (ASCP), Tricore Reference Laboratories
- The Important Differences Between Observational and Implementation Studies
Allan Jaffe, MD, Mayo Clinic
- Beyond the Lab: Transforming Patient Care Through Impactful Testing Outcomes
Zhen Zhao, PhD, DABCC, FADLM, Weill Cornell Medicine
32444 Implementation of Equations to Estimate Glomerular Filtration Rate at a Pediatric Institution
Moderator: Angela Ferguson, PhD, DABCC, FADLM, Children's Mercy Hospital
Speakers:
- Reporting Estimate Glomerular Filtration Rate in Pediatrics: A Laboratory Perspective
Angela Ferguson, PhD, DABCC, FADLM, Children's Mercy Hospital
- Reporting Estimate Glomerular Filtration Rate in Pediatrics: A Clinician Perspective
Darcy Weidemann, MD, MHS, Children's Mercy Kansas City
Session Highlight
32445 Pathogen Detection, Machine Learning, or Host Biomarkers: Can Any of These Technologies Help Address the Challenge of Sepsis?
Speakers will highlight recent innovations in sepsis risk stratification tools and molecular detection technologies that have shown potential for rapid, sensitive, and cost-effective diagnosis of septic patients.
Moderator: Nathan Ledeboer, PhD, ABMM, FAAM, Medical College of Wisconsin
Speakers:
- Transcriptomics, Cell Structure, or Machine Learning: An Overview of the Tools for Detection of Septic Patients
Nathan Ledeboer, PhD, ABMM, FAAM, Medical College of Wisconsin
- The Need for Sepsis Biomarkers and Rapid Pathogen Detection: A Perspective From the Emergency Department
Chadd Kraus, DO, Lehigh Valley Health Network
- Is Sepsis Detection the Next Troponin and Can the Laboratory Provide the Results at the Time of Need?
Alison Woodworth, PhD, DABCC, FADLM, CTI Clinical Trials & Consulting
32446 Automating Digital Workflows in the Clinical Laboratory Using Robotic Process Automation
Moderator: Simone Arvisais-Anhalt, MD, University of California, San Francisco
Speakers:
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Simone Arvisais-Anhalt, MD, University of California, San Francisco
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Daniel Holmes, MD, St Paul's Hospital Providence Health Care
ADLM-ADA Joint Session
32447 Gestational Diabetes Mellitus: Thinking Beyond Current Testing Guidelines
Moderator: David Sacks, MB ChB, FRCPath, National Institutes of Health
Speakers:
- Chill Out! Missed Diagnoses of Gestational Diabetes Mellitus Due to Lax Specimen Handling
Michael Turner, MD, University College Dublin
- Can We Move Beyond the OGTT for Diagnosis of Gestational Diabetes Mellitus and Postpartum Testing?
Cuilin Zhang, PhD, Yong Loo Lin School of Medicine/National University of Singapore
- Is 24 Weeks Too Late? Who Should Be Screened Earlier and What Is the Impact on Outcomes?
David Simmons, MBBS, MA, Western Sydney University
2:30 p.m. – 4 p.m.
32221 Responding to the Threat of Xylazine and Drug Supply Adulteration: Clinical Testing Strategies and Empowering Point-of-Service Community Drug Checking
Moderator: Adina Badea, PhD, DABCC, Lifespan Health/Rhode Island Hospital/Brown University
Speakers:
- Best Practices and Testing Strategies in Overdose Patient Management
Rachel Wightman, MD, FACMT, Alpert Medical School of Brown University
- Leveraging Clinical Comprehensive Drug Testing in the Age of Drug Supply Adulteration
Adina Badea, PhD, DABCC, Lifespan Health/Rhode Island Hospital/Brown University
- Assessing Accuracy and Utility of FTIR Testing and Xylazine Test Strips as Community Drug Checking Tools
Traci Green, PhD, MSc, Brandeis University/Rhode Island Hospital, Brown University
32222 Emerging Diagnostics to Differentiate Type 1 From Type 2 Myocardial Infarction and Acute Non-Ischemic Myocardial Injury
Moderator: Xander van Wijk, PhD, DABCC, FADLM, Van Wijk Consulting, LLC
Speakers:
- Distinguishing Type 2 Myocardial Infarction From Myocardial Injury and Type 1 Myocardial Infarction
Allan Jaffe, MD, Mayo Clinic
- Serum Biomarkers and Algorithms to Differentiate Myocardial Infarction Types
Xander van Wijk, PhD, DABCC, FADLM, Van Wijk Consulting, LLC
- Analysis of Microvesicles for Cardiac Troponin to Detect Reversible Injury and Demand Ischemia
Alan Wu, PhD, University of California at San Francisco
32223 Navigating Challenges in Tumor Marker Testing: Insights and Solutions
Moderator: Joyce Liao, PhD, DABCC, University of Washington
Speakers:
- Journey of Body Fluid Tumor Marker Testing: Crossing Sample Variability and Interference
Jonathan Genzen, MD, PhD, ARUP Laboratories
- Continuous Transitions: Strategies for Consistent Tumor Marker Testing Across Platforms
J Shirley Li, PhD, MD, DABCC, NRCC, Ohio State University Wexner Medical Center
- Beyond Intended Use: Designing Validation Protocols for Accurate Tumor Marker Testing in Diverse Patient Populations
Qian Sun, PhD, DABCC, Corewell Health
32224 International Quality Indicators: Experiences, Opportunities, and Challenges
Moderator: Vincent De Guire, PhD, MSc, Maisonneuve-Rosemont Hospital
Speakers:
- Benchmarking of Laboratory Processes: IFCC WG-LEPS Guidelines and the Canadian Experience
Vincent De Guire, PhD, MSc, Maisonneuve-Rosemont Hospital
- Benchmarking of Laboratory Processes: The Brazilian Indicators Program
Fernando Berlitz, MBA, Controllab
Session Highlight
32225 Operationalizing AI in Lab Medicine: Approaches for Effective Machine Learning Integration and Deployment
Clinical laboratories are leading the technological evolution of machine learning in healthcare but may lack practical guidance. This session will bridge that gap and provide strategies.
Moderator: Stephen Master, MD, PhD, FADLM, Children's Hospital of Philadelphia
Speakers:
- Beyond the Buzz: Practical Pathways to AI Deployment in Clinical Laboratories
Thomas Durant, MD, Yale University
- Are You Prepared? Appraisal and Evaluation of AI Applications for Laboratory Medicine
David McClintock, MD, Mayo Clinic
- From Theory to Practice: Lessons Learned in Implementation of a Machine Learning Solution for Preanalytical Error Detection
Nicholas Spies, MD, Washington University in St. Louis
32226 Improving Lead Testing Access: Leaning Into Decision Support Tools and Lead Screening by Dried-Blood Spots
Moderator: Jessica Colon-Franco, PhD, DABCC, FADLM, Cleveland Clinic
Speakers:
- Leveraging Informatics to Identify Children at Risk of Lead Toxicity and Increase Screening Rates
Roopa Thakur, MD, Cleveland Clinic
- The Role of the Clinical Laboratory in Local Lead Testing Surveillance Programs: A Pilot Study Using Dried Blood Spots
Jessica Colon-Franco, PhD, DABCC, FADLM, Cleveland Clinic
32227 Practical Update on Laboratory Testing for Bleeding Problems: Adapting to New Evidence, Guidelines and Therapies, With Illustrative Cases
Moderator: Morayma Reyes-Gil, MD, PhD, Cleveland Clinic
Speakers:
- Update on von Willebrand Disease Testing
Catherine Hayward, MD, PhD, FRCP, McMaster University
- Platelet Disorders: Diagnostic Testing
Geoffrey Wool, MD, PhD, University of Chicago
- Factor Deficiencies: Diagnostic and Treatment Monitoring Testing
Morayma Reyes-Gil, MD, PhD, Cleveland Clinic
32228 The Gift of Life: The Remarkable Role the Clinical Laboratory Plays in Organ Donation
Moderator: Amber Carriker, BS, C(ASCP), Mid America Transplant
Speakers:
- The Unique Requirements for Organ and Tissue Donor Screening Assays
Amber Carriker, BS, C(ASCP), Mid America Transplant
- Compatibility Testing: I’ll Accept That (Human and Xeno)!
Sam Ho, PhD, ABHI, Gift of Hope Organ & Tissue Donor Network
- Managing Brain Dead Donors in a Non-Traditional Setting
Selena Warden, MSc, ASCP, Southwest Transplant Alliance
32229 Advances and Limitations of Consumer-Initiated Laboratory Testing
Moderator: Julie Shaw, PhD, The Ottawa Hospital University of Ottawa/Eastern Ontario Regional Laboratories Association
Speakers:
- How Is This Lab Different From Yours? The Ins and Outs of a Laboratory Where Consumer-Initiated Testing Is the Norm
Dina Greene, PhD, DABCC, University of Washington.
- Your Results Are Back! Clinical Support for Consumer-Initiated Testing
Avantika Waring, MD, 9amHealth
- Ethical Considerations for Consumer-Initiated Testing
Melissa Budelier, PhD, DABCC, TriCore Reference Laboratories
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Tuesday, July 30
10:30 a.m. –12 p.m.
33101 ADLM Healthcare Forum: The Impact of LDT Oversight on the Delivery of Care
Moderator: Joe Wiencek, PhD, DABCC, NRCC, FADLM, Vanderbilt University Medical Center
Speakers:
- The Necessity of LDTs in Pediatric Care: Lack of Access Leads to Compromised Patient Care
Patricia Jones, PhD, DABCC, FADLM, University of Texas Southwestern Medical Center
- LDT Oversight by the Experts: Finding Alternatives to the Proposed FDA Rule
Dennis Dietzen, PhD, DABCC, FADLM, Washington University School of Medicine
33102 Clinical Laboratory Accreditation Agencies: What You Should Know Before, During, and After an Inspection
Moderator: Veronica Luzzi, PhD, DABCC, TriCore Reference Laboratories
Speakers:
- CLIA, COLA, TJC: What You Should Know but Are Afraid to Ask
Veronica Luzzi, PhD, DABCC, TriCore Reference Laboratories
- Navigating Through Intentions of Regulatory Checklists
Jude Abadie, PhD, DABCC, DABMGG, FADLM, FACMG, Texas Tech University Health Sciences Center
- Enhancing Laboratory Quality with ISO15189
Alejandro Molinelli, PhD, NRCC, St. Jude Children's Research Hospital
ADLM-Endocrine Society Joint Session
33103 Clinical Assay Issues: What Endocrinologists Will Ask You
Moderator: David Sacks, MB ChB, FRCPath, National Institutes of Health
Speakers:
- Eucalcemic Hyperparathyroidism: Is it Primary Hyperparathyroidism?
Joseph Shaker, MD, Medical College of Wisconsin
- How to Accurately Diagnose Growth Hormone Abnormalities?
Jeannette Goguen, MD, St Michael's Hospital
- Antibodies Guiding the Diagnosis of Hyperglycemia and Hypoglycemia
Adrian Vella, MD, Mayo Clinic
33104 Clinical Chemistry Journal Hot Topics: A Point-Counterpoint on LDL-C Equations
Moderator: Jason Park, MD, PhD, DABCC, Children's Medical Center
Speakers:
- The Clinical Importance of LDL-C
Ian Young, MD, Queen's University Belfast
- Calculation of LDL-C Using the Martin-Hopkins Equation
Seth Martin, MD, MHS, Johns Hopkins University School of Medicine
- Calculation of LDL-C Using the Sampson-NIH Equation
Alan Remaley, MD, NIH
Special Interactive Session
33105 Improv and the Art of Medicine: Adaptable Skills for an Uncertain World
Life is unpredictable. Improvisation is a skill that can be used to respond to difficult unexpected challenges and conversations. Join this interaction session to learn how.
Speaker: Belinda Fu, MD, Mayutica Institute / TheImprovDoc
33106 Dipping Your Toes Into the Data Analytics Pool: A Session With Laboratory Professionals Working on Informatics Projects
Moderator: Mark Cervinski, PhD, DABCC, FADLM, Dartmouth-Hitchcock Medical Center
Speakers:
- Through the Shallows: Regional Quality Control and Calibrations
Dustin Bunch, PhD, DABCC, Nationwide Children's Hospital
- Developing Machine Learning Models to Improve Test Utilization and Laboratory Stewardship
He Yang, PhD, DABCC, Weill Cornell Medicine
- From Idea to Beta Testing: Use cases to build your Analytics Skills
Steven Cotten, PhD, DABCC, NRCC, FADLM, University of North Carolina at Chapel Hill
33107 Capital Purchases and Cost Accounting for Lab Leaders: Essential Skills for Demonstrating the Value of the Laboratory
Moderator: David Shiembob, BS, MBA, C (ASCP), ARUP Laboratories
Speakers:
- Making the Case for Capital Purchases: Translating Ideas Into Action
David Shiembob, BS, MBA, C (ASCP), ARUP Laboratories
- The Cost of Doing Business: Demystifying Lab Cost Analysis
Zachary Zaret, MHA, DLM(ASCP)CM, ARUP Laboratories
33108 Informatics and Technological Approaches for Addressing the Challenges of Large-Scale Genomic Testing
Moderator: Kai Lee Yap, PhD, DABMGG, Ann & Robert H Lurie Children's Hospital of Chicago
Speakers:
- Validation of Natural Language Processing (NLP) Algorithms for Deep Phenotyping of Patients Receiving Genomic Testing
Kai Lee Yap, PhD, DABMGG, Ann & Robert H Lurie Children's Hospital of Chicago
- Overcoming the Challenges of Whole Exome Sequencing for the Diagnosis of Patients With Monogenic Kidney Disease
Daniela del Gaudio, PhD, DABMGG, University of Chicago
- Long-Read Whole Genome Sequencing for Solving Undiagnosed Rare Diseases
Danny Miller, MD, PhD, DABMGG, University of Washington
33109 ADLM Academy Distinguished Abstracts: Innovative Applications for Today and Emerging Discoveries for Tomorrow
Moderator: Gyorgy Abel, MD. PhD, DABCC, FADLM, Lahey Hospital & Medical Center, Beth Israel Lahey Health
Speakers: ADLM Academy Distinguished Abstract award-winners to be determined
2:30 p.m. – 4 p.m.
33221 Speaking Their Language: Communicating to Hospital Leadership the Essential Role of the Laboratory in Value-Based Care
Moderator: James Crawford, MD, PhD, Northwell Health
Speakers:
- Working With Hospital and Health System Leadership: The Northwell Health Laboratories Story
Dwayne Breining, MD, Northwell Health
- Importance of the Hospital and Health System Laboratory From an Administrators Perspective
Alex Hellinger, DPT, MBA, FACHE, Northwell Health
33222 You Did What Now? Addressing Questionable Laboratory Practices
Moderator: Grace Williams, PhD, DABCC, Virginia Commonwealth University
Speakers:
- Resolving Laboratory Errors
Jacqueline Hubbard, PhD, C(ASCP), DABCC, NRCC, Three Rivers Diagnostics
- Resolving Noncompliant Laboratory Procedures
Grace Williams, PhD, DABCC, Virginia Commonwealth University
33223 Unexpected Toxicology Results as Real-Time Opportunities for Collaboration
Moderator: Nicholas Heger, PhD, NRCC, Tufts Medical Center
Speakers:
- Unexpected Negatives
Nicholas Heger, PhD, NRCC, Tufts Medical Center
- Unexpected Positives
Danyel Tacker, PhD, DABCC, FADLM, West Virginia University
- Practical Considerations for LC-MS-Based Toxicology Analysis
Steven Conklin-Lopez, BS, PhD, NRCC, Labcorp
Session Highlight
33224 Acute Kidney Injury Biomarkers: Ready for Primetime?
Learn the latest on the shifting paradigm in AKI biomarkers through case-based discussion to see how limits of "one size fits all" and advances in new diagnostic criteria impact outcomes.
Moderator: Robert Nerenz, PhD, DABCC, Medical College of Wisconsin
Speakers:
- Moving Beyond Creatinine: A New Era in Acute Kidney Injury Diagnosis
Robert Nerenz, PhD, DABCC, Medical College of Wisconsin
- CXCL9 for Diagnosis of Acute Interstitial Nephritis
Dennis Moledina, MD, PhD, FASN, Yale School of Medicine
- NGAL for Acute Kidney Injury Diagnosis in Cirrhotic Patients
Kevin Regner, MD, MS, FASN, Medical College of Wisconsin
33225 Care Continuum: How Hematologists, Laboratorians, and Transfusion Medicine Physicians Partner to Diagnose, Manage, and Support Patients with Sickle Cell Disease
Moderator: Zahra Shajani-Yi, PhD, DABCC, NRCC, FADLM, Labcorp
Speakers:
- The Hematologist’s View: Clinical and Hematological Effects of Sickle Cell Disease
Susanna Curtis, MD, PhD, Icahn School of Medicine at Mt Sinai,
- The Laboratory View: Laboratory Methods Used to Diagnose and Manage Sickle Cell Disease
Sean Campbell, PhD, DABCC, FADLM, Montefiore Medical Center
- The Transfusion Medicine Physician's View: Transfusion and Apheresis in Sickle Cell Disease Care
Caroline Alquist, MD, PhD, F(ACHI), FCAP, University of Cincinnati
33226 Getting Started with Data Analytics: Indirect Reference Intervals as a Case Study
Moderator: Sarah Wheeler, PhD, FADLM, University of Pittsburgh Medical Center
Speakers:
- Accessing and Analyzing Laboratory Data: Tools, Techniques, and Tips
Sarah Wheeler, PhD, FADLM, University of Pittsburgh Medical Center
- Exploring Data Analytics Through Case Studies in Indirect Reference Interval Applications
Kelly Doyle, PhD, DABCC, FADLM, ARUP Laboratories
- Systematic Ways to Avoid Fantasy and Self-Deception With Indirect Reference Interval Determination
Daniel Holmes, MD, St Paul's Hospital Providence Health Care
33227 Metabolic Emergencies in the Pediatric Patient: Laboratory Differentiation of Inborn Errors of Metabolism and Acute Drug Exposure
Moderator: Kara Lynch, PhD, DABCC, FADLM, University of California, San Francisco
Speakers:
- Diagnostic Evaluation of Pediatric Patients with Acute Metabolic Derangements
Kara Lynch, PhD, DABCC, FADLM, University of California, San Francisco
- Laboratory Game of Clue: Metabolic Disorder or Exogenous Exposure?
Sydney Strickland, PhD, DABCC, Labcorp
33228 Microbes Meet Machines: Total Laboratory Automation in Clinical Microbiology
Moderator: Vincent Streva, PhD, Northwell Health Laboratories
Speakers:
- Digital Bacteriology: Lessons Learned From Implementing the Copan WASPLab Full Lab Automation System
Caitlin Otto, PhD, New York University Tisch Hospital
- Adventures in Automation: Navigating Challenges and Successes with the BD Kiestra Total Lab Automation System
Jamie Lemon, PhD, Northwell Health Laboratories
33229 Navigating Constitutional Genomic Disorders Throughout the Exome
Moderator: Jude Abadie, PhD, DABCC, DABMGG, FADLM, FACMG, Texas Tech University Health Sciences Center
Speakers:
- Building Exome Testing Infrastructure to Explore Clinical Genetic Cases
Joel Lefferts, PhD, DABCC, ABB, Dartmouth-Hitchcock Medical Center
- Interpretation of Exome Sequencing to End the Diagnostic Odyssey
Jude Abadie, PhD, DABCC, DABMGG, FADLM, FACMG, Texas Tech University Health Sciences Center
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Wednesday, July 31
10:30 a.m. – 12 p.m.
34101 International Regulatory Considerations for Laboratory-Developed Tests: Opportunities and Risks for Patient Care
Moderator: Christina Lockwood, PhD, DABMGG, DABCC, University of Washington
Speakers:
- Impact of Diagnostic Regulations on Laboratory-Developed Tests in the United States
Christina Lockwood, PhD, DABMGG, DABCC, University of Washington
- Regulatory Considerations for Laboratory-Developed Tests From the European Perspective
Patrick Bossuyt, PhD, University of Amsterdam/Amsterdam UMC
- Off-Label Diagnostics: An Analogy to Individualized Therapeutic Medicine: The Oncology Case
Ettore Capoluongo, PhD, University of Naples Federico II
Session Highlight
34102 Ensuring Equity and Fairness in Machine Learning and Data Analytics
Machine learning and data analytics promise to improve the value and efficiency of laboratory testing. However, there are threats of these tools generating unfair predictions and perpetuate disparities. Learn how this can happen and how to avoid.
Moderator: Mark Zaydman, MD, PhD, Washington University in St. Louis
Speakers:
- Conceptualizing and Measuring Algorithmic Fairness
Mark Zaydman, MD, PhD, Washington University in St. Louis
- How Machine Learning Algorithms Incorporate Biases and Make Unfair Predictions
Weishen Pan, PhD, Weill Cornell Medicine
- Strategies and Tools for Engineering Algorithmic Fairness
Jenny Yang, MSc, BASC, University of Oxford
34103 Changing the Sexually Transmitted Infection Control Paradigm: Novel Diagnostic and Treatment Strategies
Moderator: Barbara Van Der Pol, PhD, MPH, University of Alabama at Birmingham
Speakers:
- Changing Access to Sexually Transmitted Infection Diagnostics: Improving Reach With New Technologies and Applications
Barbara Van Der Pol, PhD, MPH, University of Alabama at Birmingham
- Diagnostics and Enhanced Laboratory Approaches to Combat Neisseria Gonorrhoeae Antimicrobial Resistance
Olusegun Soge, PhD, MSc, University of Washington
- Anticipating and Monitoring Antibiotic Resistance in the Era of Doxycycline PEP
Aniruddha Hazra, MD, University of Chicago Medicine
34104 Clinical Laboratory Investigation of Lipid Disorders: A Practical Approach
Moderator: Tahir Pillay, MD, PhD, University of Pretoria
Speakers:
- Laboratory Tests for Lipid Disorders: Navigating the Panels
Tahir Pillay, MD, PhD, University of Pretoria
- Practical Case Studies of Common Dyslipidemias
Patrick Twomey, MD, Chemical Pathology, St Vincent's University Hospital
- Alignment of Laboratory Testing With Management and Treatment Guidelines for Dyslipidemias
Amy Saenger, PhD, DABCC, FADLM, Hennepin County Medical Center
34105 Clinical Toxicology in the Courtroom: How to Serve as an Expert Witness
Moderator: Saeed Jortani, PhD, DABCC, FADLM, University of Louisville
Speakers:
- Presiding Judge
Eric Haner, JD, Kentucky Administrative Office of the Courts
- Defense and Plaintiff Attorneys
Bo Bolus, JD, Bolus Law Office
Matthew Gay, JD, Boehl Stopher and Graves, LLP
- Expert Witnesses
Alan Wu, PhD, University of California at San Francisco
Saeed Jortani, PhD, DABCC, FADLM, University of Louisville
34106 The Changing Landscape for Cystic Fibrosis Testing and Treatment
Moderator: Lisa Johnson, PhD, DABCC, Seattle Children's Hospital
Speakers:
- Diagnostic Guidelines and Challenges for Cystic Fibrosis
Heather Nelson, PhD, DABCC, ARUP Laboratories
- The Impact of Novel Therapies on the Laboratory Testing Results: A Collaborative Study With a Cystic Fibrosis Care Center
Tatiana Yuzyuk, PhD, DABMGG, ARUP Laboratories
- Inequalities in Cystic Fibrosis Outcomes and Care
Catherine McDonald, PhD, RDN, Primary Children’s Hospital
34107 JALM Hot Topics: Current Challenges and Future Promise in Molecular Diagnostics
Moderator: Nikoletta Sidiropoulos, MD, University of Vermont Medical Center
Speakers:
- Optimizing Molecular Diagnostics: Stewardship for Precision Testing, Minimizing Costs, and Enhancing Clinical Relevance in Infectious Disease Management
Erin Graf, PhD, D(ABMM), Mayo Clinic Arizona
- Genomic Data Optimization: Cost-Effective Utilization and Future Opportunities in Germline Sequencing for Enhanced Patient Care and Diagnostic Resolution
Ann Moyer, MD, PhD, Mayo Clinic
- Genomic Testing Equity: Ensuring Fair and Inclusive Access for All in the Pursuit of Personalized Healthcare Advancements
Nikoletta Sidiropoulos, MD, University of Vermont Medical Center
34108 Point-of-Care Testing Challenges in Traditional and Non-Traditional Settings
Moderator: Heather Stieglitz, PhD, DABCC, Ohio State University Medical Center
Speakers:
- Documenting Critical Results Without the Laboratory Information System
Heather Stieglitz, PhD, DABCC, Ohio State University Medical Center
- Influencing Without Authority: Strengthening Point-of-Care Testing Oversight Across a Healthcare System
Nichole Korpi-Steiner, PhD, DABCC, University of North Carolina, Chapel Hill
- Point-of-Care Testing in Unusual Healthcare Settings
Sarah Wheeler, PhD, FADLM, University of Pittsburgh Medical Center
2:30 p.m. – 4 p.m.
34221 Alzheimer’s Disease and the New Therapeutic Age
Moderator: Leslie Shaw, PhD, DABCC, Hospital of the University of Pennsylvania
Speakers:
- Progress on Therapeutics for Alzheimer’s Disease
Philip Lee, MD, FRCPC, St. Paul's Hospital
- Biomarkers in Alzheimer’s Disease: Learnings from Clinical Trials
Leslie Shaw, PhD, DABCC, Hospital of the University of Pennsylvania
- Genetic and Other Biomarkers for Alzheimer's Disease: Patient and Family Counseling Considerations
Emily Dwosh, BEd, MSc, UBC Hospital
34222 Best Practices and Innovations in Clinical and Technical Consultation by Medical Laboratory Professionals
Moderator: Nadia Ayala-Lopez, MLS, PhD, DABCC, MT (ASCP), NRCC, Labcorp
Speakers:
- Interpretive Comments, Clinical Decision Support, and Patient-Specific Consults to Improve Health Care Delivery
Alejandro Molinelli, PhD, NRCC, St. Jude Children's Research Hospital
- Best Practices for Actionable and Valuable Medical Laboratory Consultations
Nadia Ayala-Lopez, MLS, PhD, DABCC, MT (ASCP), NRCC, Labcorp
Session Highlight
34223 New Diagnostic Laboratory Assessments in Polycystic Ovary Syndrome
New tests are available and emerging for the diagnosis of PCOS. Also, new genome-wide association studies have expanded the polygenic risk score (PRS) for PCOS along with new criteria. Join this session to get up to date on biomarkers, diagnostics, and new criteria in PCOS.
Moderator: Corrine Welt, MD, University of Utah School of Medicine
Speakers:
- Antimullerian Hormone as a Replacement for Ultrasound in the Diagnosis of Polycystic Ovary Syndrome
Erica Johnstone, MD, MHS, University of Utah
- The Polygenic Risk Score for Polycystic Ovary Syndrome: Implications for Comorbidities
Corrine Welt, MD, University of Utah School of Medicine
- 11-Oxygenated Androgens in the Diagnosis of Polycystic Ovary Syndrome and Congenital Adrenal Hyperplasia
Richard Auchus, MD, PhD, University of Michigan
34224 Confronting a New Wave of Opioid Overdoses Through Surveillance Testing: Public Health Initiatives, Wastewater Epidemiology, and Comprehensive Drug Checking Analysis
Moderator: Adina Badea, PhD, DABCC, Lifespan Health/Rhode Island Hospital/Brown University
Speakers:
- Wastewater-Based Epidemiology for Population Level Substance Use Surveillance
Peter Chai, MD, MMS, Brigham and Women’s Hospital
- Insights From Biosurveillance: A Laboratory-Based Approach for Combating Rhode Island’s Opioid Epidemic
Louis Marchetti, PhD, TC(NRCC), Rhode Island State Health Laboratories
- High Resolution Mass Spectrometry Comprehensive Drug Testing to Characterize Local Drug Supply
Adina Badea, PhD, DABCC, Lifespan Health/Rhode Island Hospital/Brown University
34225 Adventures in Clinical Decision Support: Interactive Cases in Laboratory Stewardship
Moderator: Ronald Jackups, MD, PhD, Washington University in St. Louis
Speakers:
- Antibody Autopilot: CDS Solutions for Paraneoplastic Autoantibody Evaluations
Robert Nerenz, PhD, DABCC, Medical College of Wisconsin
- Order Incontinence: CDS Solutions for Clostridium Difficile Testing
Ronald Jackups, MD, PhD, Washington University in St. Louis
- Stop the Bleeding: CDS Solutions for Peripheral Smear Review Requests
Joseph Rudolf, MD, University of Utah School of Medicine
34226 Academy Conversations Between Clinical Laboratorians and Clinicians: Ideal Laboratory Report of Cervical Cancer Detection and Calculation of CIN3+ Risk
Moderator: Yusheng Zhu, PhD, DABCC, Pennsylvania State University Hershey Medical Center
Speakers:
- Ideal Laboratory Report for Cervical Cancer Detection and Calculation of Cervical Precancer or Cancer (CIN3+) Risk
Yusheng Zhu, PhD, DABCC, Pennsylvania State University Hershey Medical Center
- Interpretation of Risk of Cervical Precancer or Cancer (CIN3+) and Individualized Patient Management Based on Risks
Annie Leung, MD, McGill University Health Centre
34227 The Anatomy of the Grey Zone: Ambiguous Immunofixation/Immunotyping Results and How to Objectively Approach Interpretation
Moderator: Robert Maynard, PhD, NRCC, University of Kentucky
Speakers:
- Three’s Company: Electrophoresis (Gel and Capillary) and Mass Spectrometry for the Detection and Isotyping of Monoclonal Proteins
Ria Fyffe-Freil, PhD, University of Nebraska Medical Center
- So, You’re New Here? A Case-Based Approach to the Initial Detection of Monoclonal Gammopathies and Equivocal Isotyping Results
Robert Maynard, PhD, NRCC, University of Kentucky
- In It for the Long Haul: Your Toolbox for Accurately Detecting Remission and Relapse While Monitoring Patients With Monoclonal Gammopathies
Shelby Hutcherson, PhD, DABCC, Memorial Sloan Kettering Cancer Center
34228 Current and Future State of Metagenomics for Infectious Diseases Testing
Moderator: David Gaston, MD PhD, Vanderbilt University Medical Center
Speakers:
- Leveraging Clinical Impact With Metagenomic Testing
Esther Babady, PhD, D(ABMM), FIDSA, Memorial Sloan Kettering Cancer Center
- Roadmap for the Future: Evidence Generation and Optimizing Diagnostic Integration
David Gaston, MD PhD, Vanderbilt University Medical Center"
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Thursday, August 1
10:30 a.m. - 12 p.m.
Session Highlight
35101 Effective Communication with C-Suite Executives: A Chief of Operations and a Department Chair Perspective
Experts share practical administrative and leadership insights for developing collaborations among laboratory medicine professionals and C-suite executives on topics that include budget, business plan development, relative value units (RVUs), staffing, and more.
Moderator: Victoria Zhang, PhD, MBA, DABCC, FADLM, University of Rochester Medical Center
Speakers:
- Overview of Healthcare Leadership Structure and C-Suite Functions
Victoria Zhang, PhD, MBA, DABCC, FADLM, University of Rochester Medical Center
- Effective Communication With Hospital C-Suite Executives: A Chief of Operations Perspective
Kathy Parrinello, PhD, RN, University of Rochester Medical Center
- Effective Communication With Hospital C-Suite Executives: A Department Chair Perspective
Bruce Smoller, MD, University of Rochester Medical Center
35102 Preeclampsia in the Unites States: Clinical Details, Best Practices in Laboratory Medicine, and Impact of Foundational Support
Moderator: Sydney Strickland, PhD, DABCC, Labcorp
Speakers:
- Clinical Features and Presentation of Preeclampsia
Emily Rosenfeld, DO, Rutgers Robert Wood Johnson Medical School
- Laboratory Testing to Screen Women for Development of Preeclampsia and Progression to Severe Features
Sydney Strickland, PhD, DABCC, Labcorp
- Current State of Preeclampsia Within the US
Laney Poye, MIA, Preeclampsia Foundation
35103 Primer on Regulatory Aspects of In Vitro Diagnostics: How to Make Sense of the Alphabet Soup
Moderator: William Clarke, PhD, MBA, DABCC, FADLM, Johns Hopkins University School of Medicine
Speakers:
- Premarket Approvals and 510(k)s: How Commercial Diagnostics Work Their Way Through the US FDA Process
Salvatore Salamone, PhD, Saladax Biomedical Inc
- CPTs, PLAs, and the CLFS: How Clinical Test Reimbursement is Determined
William Clarke, PhD, MBA, DABCC, FADLM, Johns Hopkins University School of Medicine
- LDTs, CLIA, and the FDA: The Regulatory Landscape and the Implications of Change
Stephen Master, MD, PhD, FADLM, Children's Hospital of Philadelphia
35104 The Toxicological Problem Accumulating Inside of Us All: Breaking Down the Uses, Abuses, and Growing Public Health Concerns over PFAS
Moderator: Frederick Strathmann, PhD, MBA, DABCC, MOBILion
Speakers:
- The Use of High Resolution Mass Spectrometry for the Discovery of Novel PFAS
Mark Strynar, PhD, US Environmental Protection Agency
- PFAS Human Exposure, Health Impacts, Consumer Product Testing, and Risk Communication
Jenna Hua, PhD, Million Marker
- PFAS Pharmacokinetics and Laboratory Monitoring
Laura Labay, PhD, ABFT, DABCC, NMS Labs
35105 The Use of Intelligent Algorithms and AI in Pathology: Applications and Apprehensions
Moderator: Lauren Starbrook, MSc, DClinSci, New Cross Hospital
Speakers:
- Intelligent Algorithms in Biochemistry: Improving the Diagnosis of Familial Hypercholesterolaemia
Lauren Starbrook, MSc, DClinSci, New Cross Hospital
- Leveraging Machine Learning to Improve Detection of Analyzer Errors in a Busy Automated Laboratory
Tejas Kalaria, MD, MRCP, FRCPath, Black Country Pathology Services
- Is ChatGPT Capable of Producing Court-Ready Reports in Post-Mortem Cases?
Kate Rice-Davies, University Hospitals Leicester NHS Trust
35106 A Pathway Towards Greater Sustainability in Lab Medicine
Moderator: Joe Wiencek, PhD, DABCC, NRCC, FADLM, Vanderbilt University Medical Center
Speakers:
- Advancing Sustainability Practices in Clinical Chemistry
Joe Wiencek, PhD, DABCC, NRCC, FADLM, Vanderbilt University Medical Center
- Tools for Building a Global Culture of Sustainability in Science
James Connelly, My Green Lab
- Exploring the Paradox of Harming Health by Delivering Health Care
Ilyssa Gordon, MD, PhD, Cleveland Clinic
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